Dow Jones Today | US Stock Market Live: Wall Street's main indexes traded lower on Tuesday after hitting a series of record highs, while blowout results from Hewlett Packard Enterprise and a funding commitment from Alphabet underscored investor confidence in t... Dow Jones Today | US Stock Market Live: Wall Street's main indexes traded lower on Tuesday after hitting a series of record highs, while blowout results from Hewlett Packard Enterprise and a funding commitment from Alphabet underscored investor confidence in the AI buildout. Susannah Streeter, chief investment strategist at Wealth Club Shares of Fulcrum Therapeutics plunged 52% on Tuesday after the company said it would abandon development of its experimental sickle-cell disease drug following cancer-risk concerns raised by the U.S. FDA, and explore strategic options including a potential sale or merger. The oral drug, pociredir, was being tested to treat sickle-cell disease, an inherited blood disorder that can trigger pain, anemia and organ damage and reduce life expectancy. The setback adds to a string of challenges in sickle-cell drug development. In 2024, Pfizer withdrew its approved therapy Oxbryta and stopped related studies over safety concerns. Read More Anthropic on Tuesday gave approximately 150 organizations around the world access to Mythos, its powerful new AI model whose rapid ability to identify weaknesses in computer security has sparked global concern. The California AI company had initially restricted access to Mythos in early April, after tests showed the model was extraordinarily good at finding security holes in software code -- identifying thousands of them in a short period of time. Copper rose to a more than two-week high on Tuesday as tariff uncertainty and tightening supply outside the United States supported prices, while aluminium struck a more than four-year peak. Benchmark three-month copper on the London Metal Exchange was up 1% at $13,970 a metric ton in official open outcry activity. It earlier touched $13,994, its highest since May 14. Investors are awaiting a recommendation from the U.S. Department of Commerce by the end of the month on possible tariffs on imports of refined copper. The prospect of such a duty helped spur prices last year but ultimately did not materialise. Meta is expanding its content settings for teen accounts on Instagram, Facebook and Messenger globally to ensure age-appropriate experiences for younger users, it said on Tuesday, as social media platforms face growing scrutiny about child health and safety. The initiative, initially launched in select countries last October, sought to prevent children from accessing inappropriate content. Meta also announced a new feature on Instagram designed to diversify content seen by teens and prevent repetitive exposure to certain themes. Comments are moderated and will be allowed if they are about the topic and not abusive. Choose your reason below and click on the Report button. This will alert our moderators to take action Your Reason has been Reported to the admin. Dow Jones Today | US Stock Market Live: Wall Street's main indexes traded lower on Tuesday after hitting a series of record